OMass: Preclinical Toxicologist (Principal Scientist/Associate Director DOE)

Essential Experience, Skills and Qualities

• A degree or equivalent in Biology, Toxicology, Biomedical Science, Pharmacology or related pharmaceutical science

• Significant amount of relevant industry, biotech or CRO experience with a track record of contributing to study designs and interpretation of data.

• High degree of knowledge in preclinical safety assessment studies supporting IND-enabling packages and relevant regulatory requirements

• Experience in managing safety assessment studies either as Sponsor Monitor, Deputy Study Director or Study Director level.

• A strong knowledge of regulatory guidelines on study conduct

• High level of analytical and problem-solving skills, and the ability for lateral thinking

• Responsible and focused approach to independent and collaborative work, with the ability to prioritise and deliver high quality work to deadlines.

• Innovative and ambitious mindset, with an inquisitive and agile approach to problem-solving and overcoming technical challenges; motivated to continuously learn and take on challenges.

• Caring and inclusive; respectful and receptive to others’ diverse ideas, experience and perspectives, and enjoys working collaboratively with others as a team.

• Excellent communication skills, both written and verbal with high attention to detail.

Preferred Experience and Skills

• Experience at Study Director/Deputy Study Director level and/or Sponsor Monitor in preclinical toxicology and safety pharmacology studies supporting IND-enabling packages

• Experience in exploratory/investigative preclinical toxicology

• Toxicokinetic analysis/experience in the use of Phoenix WinNonLin

• Ability to navigate and work effectively in a fast-paced, matrix-team work environment

• Experience in managing and working with external contract research organisations

• A creative and strategic thinker who can enthuse the DMPK and Toxicology group and the wider OMass team with innovative ideas

• Strong organisational skills with an ability to prioritise work accordingly to project goals and take responsibility for the timely delivery of objectives

Role Responsibilities

• Provide expertise in preclinical studies to support a range of drug development projects working from Candidate Selection and beyond

• Work with the Development team and Director of DMPK/Toxicology to resolve or risk-mitigate project-related safety challenges in the design and optimisation of drug discovery molecules

• Design, commission and conduct appropriate experimental studies to support compound development nomination, project progression

• Act as Sponsor Study contact/co-ordinator for day-to-day correspondence between specialist CROs and OMass development programs

• Be involved in vendor visits to aid selection and build collaborative approaches

• Design preclinical toxicology/safety pharmacology through specialist contract research organisations

• Interpret data and write and present project reports

• Share information openly and work collaboratively with other departments to help advance different projects and achieve company goals

• Promote and adhere to OMass’ values of being Ambitious, Responsible, Innovative, Focused, Caring and Collaborative

OMass Benefits

OMass offers an excellent benefits package including:

• Private Health Insurance

• Health and wellbeing cashback scheme

• Life Assurance and Income Protection

• Participation in Employee Equity Scheme

• 25 days annual leave, plus bank holidays

• Pension Scheme offering 6% employer contribution

• Learning and Development Opportunities

• Company social events

Any queries relating to the role can be sent to hr@omass.com.

OMass Therapeutics values diversity and is committed to equality of opportunity, we also have full responsibility to ensure that all employees are eligible to work and live in the UK.