Latest News

The listing below shows our latest News Items and is updated regularly.  If you wish to post a news item please select the 'Post News' button on the right.  The displayed news feed starts on 1st August 2016.  Older items can be found here.

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Design and MinION testing of a nanopore targeted gene sequencing panel for chronic lymphocytic leukemia

We report a customized gene panel assay based on multiplex long-PCR followed by third generation sequencing on nanopore technology (MinION), designed to analyze five frequently mutated genes in chronic lymphocytic leukemia (CLL): TP53, NOTCH1, BIRC3, SF3B1 and MYD88. For this purpose, 12 patients were selected according to specific cytogenetic and molecular features significantly associated with their mutational status. In addition, simultaneous analysis of the targets genes was performed by molecular assays or Sanger Sequencing. Data analysis included mapping to the GRCh37 human reference genome, variant calling and annotation, and average sequencing depth/error rate analysis. The sequencing depth resulted on average higher for smaller amplicons, and the final breadth of coverage of the panel was 94.1%. The error rate was about 6% and 2% for insertions/deletions and single nucleotide variants, respectively. Our gene panel allows analysis of the prognostically relevant genes in CLL, with two PCRs per patient. ...

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Rapid Diagnosis of Lower Respiratory Infection using Nanopore-based Clinical Metagenomics

In the latest edition of Oxford Nanpore's newsletter please take a look at an article: Rapid Diagnosis of Lower Respiratory Infection using Nanopore-based Clinical Metagenomics

Lower respiratory tract infections are the leading cause of death from infectious disease worldwide, causing three million deaths in 2016. A wide range of pathogens cause these infections, making quick diagnosis and prescribing decisions a challenge.

Using the MinION, Charalampous et al. developed a pipeline that was capable of removing up to 99.99% of host nucleic acids from the clinical samples, was 96.6% concordant with culture in terms of pathogen detection, and could accurately detect resistance genes within six hours.

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OBN Awards: 2018 Finalists announced

We are delighted to announce our 2018 OBN Award Finalists.  This is the 10th anniversary of the OBN Awards, the life sciences industry’s most highly regarded awards event.  2018 was another record breaking year, with award entries up over 40% on 2017.  

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The pricing and reimbursement related solutions to organisations in the life sciences industry.

It is not enough for companies to gain regulatory approval in order to gain market access. Almost all new pharmaceutical products need to undergo value assessment by reimbursement authorities to gain market access and return of investment. Almost every country now has such an authority in place, including the UK, Germany, France, Italy, Spain and the USA.

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Exosome Isolation Manufacturing & Characterization

AMSBIO has announced an exosome isolation, manufacturing and characterization service to enable R&D groups to accelerate their discovery and development activities.

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Powerful CRISPR/Cas9 Gene Editing Kits

AMSBIO has introduced new CRISPR / Cas9 editing kits for gene knock-out, gene knock-in and gene mutation applications.

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Silence Therapeutics Appoints David Horn Solomon as Chief Executive Officer

Silence Therapeutics plc, a leader in the discovery and development of novel RNA therapeutics announces today the appointment of Dr David Horn Solomon as its new Chief Executive Officer (CEO) effective immediately.  David will head the Leadership Team and joins the Board of Directors. 

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Article on Sterility Testing Environments and the Vital Role of Isolators

Wickham Laboratories is pleased to announce our latest article published by Cleanroom Technology, “Isolator sterility put to the test,” written by our Sterility Section Head, Stacey Orley.

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AMSBIO Launch New Screening Company

ScreenIn3D (Glasgow, UK) is a new joint venture company set up by AMSBIO and the University of Strathclyde exploiting the latest advances in microfluidics and 3D culture to develop a novel microfluidic screening platform.

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Isansys Wireless Patient Monitoring Technology Wins Business Award For Making a “Real Difference to People’s Lives”

Isansys Lifecare wins Best Use of Technology award at the Thames Valley Chamber of Commerce Business Awards

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OBN aims to provide sector NEWS that is relevant to our Membership. We filter information from a variety of sources, publish items ourselves and will publish items of News from our Members. Press releases about OBN can be found here.