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From the monthly archives: August 2020

We are pleased to present below all posts archived in 'August 2020'. If you still can't find what you are looking for, try using the search box.

Data Manager

We're looking for a Data Manager to join our team at Enara Bio!

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Scientist / Senior Scientist, Immunology (|NGS)

We are seeking a hands-on Scientist / Senior Scientist with expertise in Immunology and Genomics who is a self-starter, proactive and would like to work in a dynamic environment of a start-up. The successful candidate will investigate the regulation of the non-coding genome in lymphocyte subsets using state of the art genomics approaches whilst also developing new ones. You will collaborate closely with other experimental and data scientists to guide drug target discovery efforts. You will provide significant conceptual input into experimental design and analysis plans and engage in cross-functional discussions. You will have an integral role in the venture, take ownership of the work and demonstrate an exceptional work ethic. 


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Machine Learning Engineer / Snr. Machine Learning Engineer

NUCLEOME THERAPEUTICS is an exciting new venture that just spun out from a decade of research at Oxford University with the aim to unlock the non-coding part of the genome to help deliver life changing treatments. 

We are building a passionate, creative and dedicated multi-disciplinary team of scientists with expertise in gene regulation, genomics, machine learning, data analysis and software development. Whose mission is to decode and mine the regulatory “dark matter” of the human genome to transform drug target discovery. We are building a rewarding and fun environment where people embrace creative ways of thinking, take smart risks, and feel empowered to make a difference. 

We are looking for Machine Learning Engineer/ Senior Machine Learning Engineer who loves to mine information from complex datasets, is a self-starter, proactive and want to work in a dynamic environment of a start-up. As an early member of the team, you will have an integral role in the venture and take ownership of the work. 

You will design and implement novel Machine Learning models in order to identify the sequences in our genomes that underlie human disease and guide therapeutic development. 

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Formulation Scientist

Formulation Scientist Permanent South Wales Attractive salary dependant upon experience Study, formulation and development of novel long-acting, injectable biopharmaceuticals, the role will need to be creative and able to work well with other functions. Working across a mixture of early stage formulation discovery projects, interpreting Quality Target Product Profiles, the role is required to apply robust and innovative scientific approaches to development of novel parenteral formulations. Design and execution of pre-formulation studies for protein and small molecule APIs. Design and development of long-acting polymer-based formulations that exploit the unique benefits of the production process. An understanding of polymer and protein chemistry and compounding is required along with an understanding of drug development pathways. Requirements: BSc in Pharmacology, Pharmaceutical Sciences, or other related subject. The candidate is required to have a background in preparation, ma ...

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Principal Scientist, Immunology

Enara Bio™ (formerly known as Ervaxx) is a science-led company targeting the T-cell/cancer cell interface (the “immune synapse”) to develop new targeted cancer immunotherapies designed to treat a broad patient population.  Our focus is the development of novel T-cell therapies based on complementary and proprietary insights from interrogating the immune synapse from both angles – on the tumor side, a growing set of novel tumor-specific targets; and on the T-cell side, a set of robust T-cell receptors (TCRs) with potent tumoricidal activity.





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Peptide Chemist

I am recruiting for an organic chemist to join a small but expanding company in the East Midlands (Leicestershire) area. You will be responsible for synthesizing peptides (both catalogue and custom) using automated peptide synthesizers and manual procedures, cleave peptides from resin supports, purification and analysis using HPLC and mass spectrometry (LC-MS, MALDI) and carrying out post synthesis modifications. Other responsibilities: Performing laboratory investigations for any Out-of-Trend, Out-of-Specification or Atypical Results as per SOP’s to ensure the root cause is identified and remedial action is taken Develop new analytical techniques for the analysis of peptides Documenting all work as per SOP’s and GLP Ensuring all working copies of documents are stored appropriately and that no unauthorized changes to the document are made after validation Interpret data and reported scientific results Liaised with customers, staff and suppliers Used and developed non-standa ...

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Sterile Manufacturing TeamLeader/Supervisor/Manager

Salary up to 40K DOE.  Leicestershire A great opportunity for you to step into a more senior position. Due to an increase in sterile manufacturing at my client they are looking to take on someone with previous sterile manufacturing experience to expand their teamThe Sterile manufacturing unit can manufacture up to Class A and has recently been expanded with new isolators.   Duties: Oversee all sterile production manufacturing operations Play a key role in the manufacture of a wide range of API's and IMP's for clinical trials according to the principles of Good Manufacturing Practice (GMP). Follow required standards with respect to documentation, good housekeeping, cGMP, Health and Safety, timekeeping, regulatory legislative requirements and in accordance with the quality manual and any other company policies. Lead upcoming manufacturing campaigns through leadership of the Production Team. Work with the Quality Manager to ensure quality compliance ...

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R&D technician

A successful biotechnology company based in South Oxfordshire is currently recruiting for an R&D Scientist to join their busy Technical Team. This is a permanent role, starting as soon as possible, paying £22-25,000.

The Role:

- Operating specialist manufacturing and metrology equipment to support R&D projects
- Assisting in laboratory team projects - process improvements, quality investigations
- Maintaining technical documentation - quality records, production batch details, etc.

The Person:

- EITHER Scientific degree OR previous relevant experience
- Excellent attention to detail, ability to work to SOPs
- Happy in a hands on laboratory based role

Contact Consultant:
Tom Pickford

 0121 726 9750

Director of Regulatory Affairs

My client is a world leader within the Biotechnology space and headquartered in Oxfordshire. They are recruiting a business critical role titled Director of Regulatory Affairs. The role itself will be responsible for the management and strategic direction of all regulatory affairs in all markets including EU, UK & US and you will be responsible for delivering and maintaining regulatory approvals and clearances for product development and related R&D projects including instruments, software and automation. The remit for this role will be extensive covering UK, US, EU and the post holder will ensure FDA and other regulatory frameworks are adhered to. The post holder will be submitting appropriate regulatory filings, supplements and pre-subs (or equivalents) to ensure business demands are met in a timely fashion in the EU, UK, US and other markets as appropriate.- You will be ensuring regulatory and related QMS (including 21 CFR 820 Quality System Regulations) requirements, processes and proc ...

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Protein Biochemist Development - Oxfordshire

My client is an industry leading Biotechnology business within the Diagnostics space with a global presence and head offices in Oxfordshire. They are going through a period of growth and looking to expand their Research & Development department with the recruitment of a Protein Scientist. The role will be to support the development of proteins including production and charactarisation. The Role - You will have the opportunity to lead the design and development of potential protein candidates. - This post holder will carry out protein expression - predomindantly flask based methods. - Hands on use of FPLC-based AKTA systems. - You will be carrying out a range of different protein purification methods including Ion exchange, size exclusion and affinity chromatography. - You will be responsible for protein stabilisation studies. Your Skills * BSc level graduate in related Life Sciences subject such as Biochemistry, Molecular Biology, Chemical Biology. * We are looking for candidates with ...

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