AMSBIO has launched a range of ELISA Host Cell Protein (HCP) detection kits that allow you to detect the presence of host cell protein impurities in your therapeutic at any phase of your product development.

Host cells used as expression systems in biopharmaceutical products contain hundreds to thousands of HCPs. It is crucial to sufficiently remove HCPs from your biologic early, as high concentrations can affect the safety and efficacy of your drug. The FDA has regulated that HCPs should be reduced to low levels.

The new HCP detection kits from AMSBIO are based on a sandwich ELISA test in a convenient 96-well plate format. The assay uses a standard for quantification which enables highly sensitive and accurate determination of HCP concentrations. These kits can be used during the protein purification process in order to monitor and optimize that step of the bioproduction workflow.
 
Based upon quick and widely familiar ELISA technology, specific HCP detection kits are available for popular expression systems including CHO, E. coli, Pichia, HEK293, and Protein A. Each kit allows quantification of up to 24 samples.  Compared to alternative HCP detection kits, those from AMSBIO offer 5-10x more sensitivity, greater antibody coverage and lower lot-to-lot variations resulting in a more consistent reliable antibody supply and a reduction in the cost of the biomanufacturing process.

For further information please visit www.amsbio.com/host-cell-protein-elisa-kits.aspx or contact AMSBIO on +44-1235-828200 / +1-617-945-5033 / info@amsbio.com.

Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading transatlantic company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products and services for research and development in the medical, nutrition, cosmetics and energy industries. AMSBIO has in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. This expertise in cell culture and the ECM allows AMSBIO to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics. 

For drug discovery research, AMSBIO offers assays, recombinant proteins and cell lines. Drawing upon a huge and comprehensive biorepository, AMSBIO is widely recognised as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical grade products for stem cell and cell therapy applications these include high quality solutions for viral delivery (lentivirus, adenovirus and adeno-associated virus) in addition to GMP cryopreservation technology.