GyreOx Ltd is a young and vibrant company with headquarters on the Harwell Research Campus in Oxfordshire, UK.  The Company has developed a proprietary combined chemistry and synthetic biology technology for the creation of highly modified macrocyclic peptides, which have the potential to address complex intracellular targets in a range of diseases of significant unmet clinical need.

We are currently recruiting for two positions, see https://www/gyreox.com/careers

Analytical Chemist (GT-2020-2)

A PhD-level scientist is sought to work on the Company’s automated platform and new drug development programmes.  This will be predominantly laboratory-based in the first instance.  It is initially part-funded by a grant from Innovate UK, but represents the potential for a future leadership role within the Company, through developing an understanding of the commercial aspects of the Company’s business.

We are looking for a skilled and experienced scientist to provide specialist analytical and mass spectrometry support.  In this position, you will be responsible for planning and undertaking routine analysis, purification, isolation and characterisation of our linear and cyclic compounds.  The candidate will support chemistry projects, characterising starting materials, intermediates and active pharmaceutical ingredients and will collaborate effectively with other colleagues.

Experience with LC and LC-MS is essential, along with the ability to trouble shoot and perform routine maintenance of HPLC equipment.

Previous experience in the pharmaceutical industry, and of the routine testing and analysis of peptide-based compounds using HPLC, LC-MS, and LC-MS/MS are desirable.

A PhD in an appropriate chemical or biochemical subject would be expected, but consideration will be given to applicants who have acquired the necessary experience within industry, particularly within drug discovery.  Knowledge of the synthesis, purification, analysis and development of peptides and macrocycles would be advantageous, but not essential.