The Associate Scientist/ Scientist – Lentiviral Vectors will be involved in a range of internal platform development and commercial projects, predominantly focused on Lentiviral vector engineering and production, and establishing stable viral packaging and producer cell lines and associated processes. The Scientist role is expected to drive and lead specific projects and areas of research from the bench, while providing support and training to Associate Scientists and technicians working in the Lentiviral Vector group, which addresses both viral vector engineering and novel-bioproduction methodologies. Oxford Genetics intends to further build its expertise over the next 6-12 months in the Viral Therapeutics field, predominantly around Lentiviral, AAV and Adenoviral vectors. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Prior experience in generating viral vectors and/or stable cell line development is highly desirable.
• Work closely with internal and external stakeholders to define project goals and deliverables, in line with the planned project objectives
• To line manage and train junior staff in laboratory techniques (as appropriate for level of appointment)
• Support line manager with customer interactions, and in ensuring smooth running of the group.
• To adhere strictly to established quality standards, essential for on-going activities
• Drafting and reviewing SOPs.
• To author scientific reports in a timely manner with high accuracy and quality.
• Promote and suggest implementation of new methods, technologies and processes to ensure best practice
• BSc/MSc in Biology, Biochemistry, Genetics or related field, with >2 years relevant experience or Ph.D with >1 year relevant experience
• Experience working in a commercial/industry environment is preferred but not essential
• Extensive track record of handling a range of adherent and suspension mammalian cell lines
• Knowledge and experience of viral vector engineering, production and characterisation, with a focus on Lentivirus
• Good experience with analytical techniques including flow cytometry and qPCR
• Ability to independently analyse, interpret and present scientific data in a clear manner
• Good communication and inter-personal skills
• Strong ability to multi-task under pressure
• Production of stable mammalian cell lines
• Use of gene editing tools for cell engineering
• Experience of cell sorting, and characterisation of clonal cell lines
• Use of robotic liquid handling and automation systems
Job type: Permanent, office and laboratory based
Hours: Full time
Salary: £24,000 – £38,000/pa, dependent on experience plus competitive benefits package
25 days Annual Leave plus Bank Holidays, Pension with matched employer contribution to 7%, Health Insurance, Group Life Cover, Glasses Vouchers, Long Service Benefits and a friendly working environment in an exciting and expanding company.
We have offices in the UK and USA. This role will be located at The Oxford Science Park, just 4 miles south east of Oxford, with parking and good public transport links from Oxford. Our UK office addresses are: Oxford Genetics Ltd, Medawar Building and Northbrook House, The Oxford Science Park, Oxford, OX4 4HG.
HOW TO APPLY
Candidates must be eligible to work in the United Kingdom without sponsorship.
Please send a CV. Your CV should include evidence that demonstrates how you meet each of the selection criteria for the post using examples of your skills and experience. This may include experience gained in employment, education, or during career breaks. Your application will be judged on the basis of how you demonstrate that you meet the selection criteria stated in the job description.
Strictly no agencies, thank you
The appointment of the successful candidate will be subject to standard pre-employment screening, as applicable to the post. This will include right-to-work in the UK, proof of identity, references and a work health assessment.
DIVERSITY AND EQUALITY OF OPPORTUNITY
We provide all our staff with a welcoming and inclusive workplace that enables and empowers everyone to develop and deliver professional excellence. We recognise diversity is vital for innovation and creativity and value each individual’s contribution. Entry into employment with Oxford Genetics and further progression will be determined by personal merit and the application of criteria related to the duties of the role. The ability to perform the role will be the primary consideration on entry into employment and to successfully pass probation.